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pandora earrings IntroductionAlthough the classic medical principle of “first do no harm” refers primarily to the balance of risks and benefits of a specific treatment, it also fits a more general approach to the practice of medicine. This was highlighted by a recent investigation of 21 hospitals in the Netherlands showing that nearly 6% of 1.3 million hospital admissions in 2004 resulted in unintentional harm to the patient.1 The combination of complexity and the potential for great harm makes medicine, especially intensive care, even more fraught with risk than other high complexity areas such as aviation.2 Although patients’ safety is increasingly recognised as an essential component in the practice of intensive care medicine, the complexity of processes and medical conditions dealt with makes the practice of this specialty vulnerable and prone to error.3 4 In the recently published first multinational sentinel events evaluation (SEE 1) study, 38.8 incidents per 100 patient days in five selected categories (drains and lines, artificial airway, equipment, handling of alarms pandora bracelets, and medication) were observed in 205 participating intensive care units.5 In that 24 hour cross sectional study, medication errors at the prescription and administration stages were reported by unit staff at a rate of 10.5 per 100 patient days. As such errors carry a particularly high potential for serious harm, this topic was chosen for the second multinational sentinel events evaluation study (SEE 2).. pandora earrings
pandora jewelry AbstractObjective To examine whether adherence to the Mediterranean diet was associated with longer telomere length, a biomarker of aging.Setting Nurses’ Health Study, an ongoing prospective cohort study of 121700 nurses enrolled in 1976; in 1989 90 a subset of 32825 women provided blood samples. Least squares mean telomere length z scores were 0.038 (SE 0.035) for the lowest Mediterranean diet score groups and 0.072 (0.030) for the highest group (P for trend=0.004).Conclusion In this large study, greater adherence to the Mediterranean diet was associated with longer telomeres. These results further support the benefits of adherence to the Mediterranean diet for promoting health and longevity.IntroductionThe traditional Mediterranean diet is characterized by a high intake of vegetables, fruits, nuts, legumes, and grains (mainly unrefined); a high intake of olive oil but a low intake of saturated lipids; a moderately high intake of fish; a low intake of dairy products, meat, and poultry; and a regular but moderate intake of alcohol (specifically wine with meals).1 Observational studies and intervention trials have consistently shown the health benefits of a high degree of adherence to the Mediterranean diet, including reduction of overall mortality2 3 4; reduced incidence of chronic diseases, especially major cardiovascular diseases5; and increased likelihood of healthy aging.6Telomeres are repetitive DNA sequences at the ends of eukaryotic chromosomes that undergo attrition each time a somatic cell divides.7 Telomeres prevent the loss of genomic DNA at the ends of linear chromosomes and in turn protect their physical integrity.8 9 Telomere attrition has been shown to be accelerated by oxidative stress and inflammation.10 11 Telomere length is considered to be a biomarker of aging; shorter telomeres are associated with a decreased life expectancy and increased rates of developing age related chronic diseases.12 13 14 Telomere length decreases with age and varies considerably among individuals.15 Studies suggest that telomere attrition is modifiable, as substantial variability exists in the rate of telomere shortening that is independent of chronological age.16 17 18 Therefore, variability of telomere length may be partially explained by lifestyle practices, including dietary patterns.19 As accelerated telomere attrition may underlie many chronic diseases, identifying modifiable factors that affect telomere dynamics is important.Given that fruits, vegetables, and nuts, key components of the Mediterranean diet, have well known antioxidant and anti inflammatory effects, and that telomere length is affected by both of these processes, we hypothesized that greater adherence to the Mediterranean diet would be associated with longer telomere length pandora jewelry.
